Medivir is a drug discovery and development company focusing on transformative cancer drugs. Our research and development are based on our extensive expertise in protease inhibitor design and nucleoside/nucleotide science. Science working wonders.

STOCKHOLM, April 20, 2021 /PRNewswire/ -- Medivir AB (Nasdaq Stockholm: Birinapant, a SMAC mimetic, is exclusively outlicensed to IGM Biosciences 

Birinapant is a SMAC mimetic that was acquired from TetraLogic Pharmaceuticals Corporation (TetraLogic) in 2016 and has since then been developed by Medivir for the treatment of solid tumors. Medivir acquired birinapant from TetraLogic in 2016. The original agreement between Medivir and TetraLogic included milestone payments with predetermined amounts as well as royalty obligations to TetraLogic if and when Medivir develops, markets or out-licenses birinapant further. Birinapant is a SMAC mimetic that was acquired from TetraLogic Pharmaceuticals Corporation (TetraLogic) in 2016 and has since then been developed by Medivir.

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Notable ongoing projects. Remetinostat, HDAC inhibitor for Cutaneous T cell lymphoma. Birinapant, SMAC mimetic for solid tumours. Birinapant är ett projekt som förvärvades 2016 från TetraLogic Pharmaceuticals Corporation och som därefter utvecklats av Medivir.

Aug 26, 2019 Medivir is a Swedish biotech company focusing on the development and However, Medivir owns all the rights to birinapant. If the results of  STOCKHOLM, April 20, 2021 /PRNewswire/ -- Medivir AB (Nasdaq Stockholm: Birinapant, a SMAC mimetic, is exclusively outlicensed to IGM Biosciences  May 8, 2019 Birinapant is being evaluated in a phase II trial with Keytruda in patients Presently, Medivir is running two clinical trials, one with birinapant in  Jun 1, 2018 TPS3131Background: Birinapant is a bivalent SMAC mimetic with activity against multiple members of the inhibitor of apoptosis protein (IAP)  May 26, 2019 2506Background: Birinapant is a bivalent SMAC mimetic targeting cIAP1.

Medivir AB (publ) (Nasdaq Stockholm: MVIR) meddelade idag att bolaget har ingått ett exklusivt licensavtal som ger IGM Biosciences, Inc. (Nasdaq: IGMS) de globala och exklusiva rättigheterna att utveckla birinapant, ett SMAC-mimetikum i klinisk utvecklingsfas som binder till och bryter ned hämmare av apoptosproteiner (IAP), vilket leder till celldöd (apoptos) i tumörceller. Kombinationen

Medivir received a payment of USD 1 million after signing, which is to be followed by an additional USD 1.5 million when IGM includes birinapant in phase I clinical trials. In addition, the The agreement provided Medivir with a payment of USD 1 million after signing, which is to be followed by an additional USD 1.5 million when IGM includes birinapant in phase I clinical trials. Birinapant was originally acquired by Medivir from TetraLogic in 2016.

Positive interim data on birinapant in combination with Keytruda® Stockholm, Sweden — Medivir AB (Nasdaq Stockholm: MVIR) today announced safety and efficacy data following an interim analysis of phase I data from the ongoing phase I/II study of birinapant in combination with MSD’s anti-PD-1 therapy, Keytruda® (pembrolizumab), in patients with advanced solid tumors who have exhausted

Banken utesluter i sin analys dock inte  Medivir omförhandlade i december avtalet med TetraLogic Pharmaceuticals bolaget ett exklusivt licensavtal med IGM Biosciences, Inc. för birinapant. Medivir  Forskningsbolaget Medivir redovisar minskande omsättning under fjärde gäller remetinostat, birinapant och MIV-711", säger vd Uli Hacksell. Positive interim data on birinapant in combination with Keytruda® Stockholm, Sweden — Medivir Köp aktier i Medivir B - enkelt och billigt hos Avanza Bank. Läs mer. Medivir beslutar om företrädesemission om cirka 170 Mkr och genom omförhandlat avtal med TetraLogic avseende birinapant. Få detaljerad information om Medivir AB ser. studier för behandling av kutant T-celllymfom (CTCL), birinapant i kombination med Keytruda (pembrolizumab) i  Medivir tecknar exklusivt licensavtal med IGM Biosciences för birinapant Inc. (Nasdaq: IGMS) de globala och exklusiva rättigheterna att utveckla birinapant,  Under året initierades dessutom en fas I/II-studie med birinapant i kombination med Mercks Keytruda® för behandling av avancerade solida  2020-12-11 08:40:00 Medivir Medivir stärker förutsättningarna för affärsutveckling genom omförhandlat avtal med TetraLogic avseende birinapant -21,43% | 8  Medivirs verkställande direktör Yilmaz Mahshid har idag meddelat styrelsen att han av Birinapant, ett SMAC-mimetikum, har utlicensierats till IGM Biosciences  För tre år sedan fick Medivir fram en riktig storsäljare.

Januari - December Finansiell sammanfattning. Nettoomsättningen uppgick till 13,9 (8,7) MSEK. Medivir Results from the completed Phase I combination study with birinapant and Keytruda will be presented during the ASCO conference in Chicago. The abstract released last night confirms what has previously been announced from Medivir.. Medivir stärker förutsättningarna för affärsutveckling genom omförhandlat avtal med TetraLogic avseende birinapant. Publicerad: 2020-12-11 (Cision) Medivir strengthens its business development possibilities through a renegotiated agreement with TetraLogic regarding birinapant Medivir omförhandlade i december avtalet med TetraLogic Pharmaceuticals Corporation gällande ersättningsmodell och nivåer för birinapant med syfte att skapa bättre förutsättningar för affärsutveckling.
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Redeye Research Note 2021/01/12. Redeye expects a strong share price reaction to the surprise deal for the oncology  10 Feb 2021 Under the terms of the agreement, Medivir has granted Ubiquigent an Birinapant, a SMAC mimetic, is exclusively outlicensed to IGM  9 Nov 2016 The acquisition includes remetinostat, a skin-directed histone deacetylase ( HDAC) inhibitor, and birinapant, a bivalent second mitochondrial  19 Apr 2021 parts of Medivir's business model, and the drug development is conducted either by Medivir or in partnership. Birinapant, a SMAC mimetic,  Accelerated bookbuild offering - Joint bookrunner Medivir completion of the MIV-711 phase IIa study and the birinapant phase I/II study, start and completion of  Birinapant is a SMAC mimetic that was acquired from TetraLogic Pharmaceuticals Corporation (TetraLogic) in 2016 and has since then been developed by  15 Oct 2018 Along with remetinostat, Medivir's clinical pipeline includes birinapant for solid tumours, MIV-818 for liver cancer and MIV-711 for osteoarthritis.

Medivir stärker förutsättningarna för affärsutveckling genom omförhandlat avtal med TetraLogic avseende birinapant. Publicerad: 2020-12-11 (Cision) Medivir strengthens its business development possibilities through a renegotiated agreement with TetraLogic regarding birinapant Medivir omförhandlade i december avtalet med TetraLogic Pharmaceuticals Corporation gällande ersättningsmodell och nivåer för birinapant med syfte att skapa bättre förutsättningar för affärsutveckling. Januari - December Finansiell sammanfattning. Nettoomsättningen uppgick till 13,9 (8,7) MSEK.
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2021-01-12

Stockholm, Sweden. • Member of the R&D Management Team, responsible for scientific review of all R&D  18 Aug 2017 Investigators running a phase 1/2 trial combining Medivir's birinapant and Merck's Keytruda enrolled the first patient in the study. Medivir sees  with FasL and birinapant (IC10) revealed additional and syner- FasL and birinapant in HNSCC cell lines. Birinapant (Medivir AB, Huddinge, Sweden) was. 26 May 2019 2506Background: Birinapant is a bivalent SMAC mimetic targeting cIAP1. Synergistic effects of combining birinapant with immune checkpoint  1 Jun 2018 TPS3131Background: Birinapant is a bivalent SMAC mimetic with activity against multiple members of the inhibitor of apoptosis protein (IAP)  12 Jan 2018 Birinapant (Medivir AB, Huddinge, Sweden) was stored according to the For combination treatment, the IC10 of birinapant and a log2 dilution  10 Nov 2020 Through the collaboration, DDD will get access to Medivir's unique For our other projects - remetinostat, birinapant and MIV-711 - we are  22 Jan 2019 birinapant sensitized tumor cells to CAR T-cell–derived TNF, plied by Medivir dissolved in 12% Captisol solution in water. (vehicle).